From 450 pounds to running 5Ks: 1000-lb Sisters' Chris Combs shares his journey

Chris Combs. Image via Instagram/@chris.combs.5243
Chris Combs (Image via Instagram/@chris.combs.5243)

Chris Combs has come a long way since his debut on 1000-lb Sisters. The 46-year-old has turned his life around in a way even he never would have believed after tipping the scales at more than 450 pounds. Inspired by his famous sisters, Amy and Tammy Slaton, Chris made the leap toward a healthier life — and never looked back. Today, he’s not only thinner, but he’s healthier and happier, and is even running 5Ks.

“This is the best journey that I've ever decided to take and stick with,”

Chris said, reflecting on how far he’s come. His path was not a straight one. There were the ups, the downs, the discouraging plateaus, but nothing quelled Chris’ resolve. Now, with the latest season 1000-lb Sisters season 7 premiere, people can see just how much life has changed for the Slaton family’s sweet-natured big brother.

Now, let’s check out the amazing transformation of Chris.


Chris faced major health struggles before joining 1000-lb Sisters

Before he began his weight-loss journey, Chris’ quality of life was far from ideal. Living with morbid obesity, he struggled daily. Moving around was painful, and he had to take up to five insulin shots a day to manage his blood sugar. Life was hard, and Chris didn’t like what he saw in the mirror.

More than anything, he was scared. After seeing his own father pass away from obesity-related complications around the same age, Chris knew he had to make a change. He didn’t want to leave his family behind the way his father had. Another motivator? His daughter had started to struggle with her own weight, and Chris wanted to show her it was possible to turn things around.

Season 7 of 1000-lb Sisters brings all of this into sharper focus. Chris wasn’t just losing weight for himself—he was fighting for his future and his family’s.


Chris started his journey at 450 pounds on 1000-lb Sisters

When 1000-lb Sisters premiered in 2020, Chris weighed over 450 pounds. It wasn’t an easy starting point, but Chris didn’t let that stop him. With the support of his family and medical team, he pushed forward.

In 2022, Chris underwent bariatric surgery, giving his weight-loss journey a major boost. By March 2024, he had lost 150 pounds. His doctor, Dr. Eric Smith, celebrated the milestone on Instagram with a striking side-by-side photo of Chris. On one side, Chris before the weight loss; on the other, a proud Chris crossing the finish line of a 5K run. The transformation wasn’t just physical. It was emotional and mental too.


Chris hit bumps in the road but kept pushing on 1000-lb Sisters

It wasn’t all smooth sailing for Chris on 1000-lb Sisters. Like many people on weight-loss journeys, he hit plateaus. After an initial burst of progress, things slowed down, and Chris found himself stuck. It was a frustrating time, especially since he was desperate to qualify for skin removal surgery.

Doctors told him he needed to lose another 60 pounds before the procedure. It was a tough pill to swallow, but Chris didn’t give up. He tightened up his diet, pushed himself at the gym, and finally reached his goal.

When he finally underwent skin removal surgery, the difference was incredible. As he left the hospital with his wife, Brittany Combs, by his side, Chris was tired but happy.

“Chris' skin removal is the icing on his weight loss journey's cake,”

said his doctor, celebrating the major step in Chris’ transformation.


Chris Combs' journey on 1000-lb Sisters is far from over

Even though Chris has hit major milestones, he’s not ready to call it quits. As fans of 1000-lb Sisters know, lasting change takes ongoing effort. Chris remains committed to maintaining his new lifestyle and staying active.

Viewers love him not just because of his physical transformation, but because of his attitude. Chris' positive energy and down-to-earth approach have made him a fan favorite on 1000-lb Sisters. His journey is a reminder that weight loss isn’t just about numbers on a scale—it’s about fighting for a better life.

Looking ahead, Chris plans to continue improving his health and possibly undergo more skin removal procedures. Whatever the future holds, one thing’s for sure: Chris has proven he’s in it for the long haul.

Fans of 1000-lb Sisters will be cheering him on every step of the way.

Edited by Sezal Srivastava