20) Charlize Theron turned down Roxie Hart in Chicago
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Charlize Theron was asked to do the role of Roxie Hart in Chicago (2002), which didn't come about because of scheduling. The role finally went to Renée Zellweger, who made an Oscar-worthy performance in return. Theron said of the situation that she was disappointed but understood why the directors had to change, and so Zellweger's iconic performance should be defined as part of her career
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