Jake Paul has unleashed a wild claim. In his telling, Mike Tyson had Parkinson's disease—until he no longer did—thanks to toad psychedelics. The YouTuber-turned-boxer decided to drop this bombshell in the middle of an interview with Adin Ross when discussing their fight on November 15, 2024, at AT&T Stadium in Arlington, Texas.
Social media weighed in, most of their comments tongue-in-cheek, after this exchange.
One X (formerly Twitter) user stated:
"You're not helping your case, Jake. 🤣 Clown show fight"
Another user added:
"Lol, Jake's gotta stop that pseudoscience talk 😂"
One user highlighted:
"So Jake Paul fought a senior citizen with Parkinson’s"
One user stressed on the most important part of the conversation:
"cured 😐"
A user added:
"so he not only fought a 60year old man but with parkinsons too damm"
A user quipped:
"Jake Paul out here turning fight promos into sci-fi scripts 💀👀"
A comment read:
"When you force an old man to take shrooms then beat him up live on TV"
A user advised:
"I wouldn’t disclose this information for any reason 😂. This is only showing that you suck for fighting a sick person."
Mike Tyson's medical history

Mike Tyson is 58, which in boxing years is about as old as you can be. He's had his own set of medical issues, including sciatica (a condition that makes sitting a contact sport) and ulcers (which almost derailed this fight when he had a nasty flare-up in May 2024).
That particular incident involved vomiting up blood and losing weight —not exactly the best training for getting into the ring.
And then there's the speculation about Parkinson's. While Tyson has never officially been diagnosed with it, medical experts have said that he does have symptoms that are similar to what other boxers, like Muhammad Ali, have had.
In The Conversation, Stephen Hughes, a senior medical lecturer at Anglia Riskin University in England, states:
“In some instances, a condition resembling Parkinson’s disease may result from loss of neurons in a part of the brain called the substantia nigra. Muhammad Ali may have been afflicted with this, but it was never confirmed.’’
Because, you know, getting punched in the head for a living isn't exactly known for being great for long-term health.
But, according to Dr. Jake Paul, none of that mattered, because psychedelics allegedly came in like a superhero and "cured" Tyson before the fight.
Paul vs. Tyson in the ring

The fight did occur. And it was... something.
Sanctioned by the Texas Department of Licensing and Regulation (which apparently saw nothing wrong with a 58-year-old man fighting a 27-year-old social media influencer), the bout came with some safety adjustments: larger gloves (14-ounce instead of 10-ounce), shorter rounds (two minutes instead of three), and eight rounds total instead of the standard 12.
All of this was intended to ensure no one was leaving in an ambulance, but it still left many people questioning whether this fight needed to have occurred at all.
Jake Paul added another win to his list. The fight went the distance, and the judges ultimately declared Paul the winner with scores of 80-72, 79-73, and 79-73.
The spectacle
As predicted, the event was a blockbuster.
72,300 fans filled AT&T Stadium, while Netflix's stream hit 65 million concurrent viewers worldwide (38 million of them in the U.S.).
Tyson made $20 million, while Paul made $40 million.
Following the fight, Paul referred to Tyson as the "G.O.A.T." and showed his respect.
Tyson, for his part, appeared content with his showing.
Whether or not toad magic had anything to do with all of this, remains a mystery. But when Jake Paul is involved, the headlines write themselves.

Your perspective matters!
Start the conversation