Online memes erupt over Karla Sofia Gascon's reaction to Conan O'Brien's joke at Oscars 2025

The 2025 Oscars were complete with glamorous moments and star-studded speeches, but let's get real: nothing had the internet buzzing quite like Conan O'Brien's amusing dig at actress Karla Sofia Gascón. O'Brien, never one to lack quick wit and savage humor, landed a lighthearted punch at Gascón in his monologue, and well, let's just say it didn't fly under the radar.

Conan said:

"Anora uses the F word 479 times. That's three more than the record set by Karla Sofía Gascón's publicist. If you are going to tweet about the Oscars, remember, my name is Jimmy Kimmel

Now, we all know the Oscars is the pinnacle of glamour and grace, but when it comes to jokes, there’s no shortage of shade, especially when Conan O’Brien is involved.

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Karla Sofia’s Reaction Goes Viral

When Conan O'Brien made the joke, the reaction was instant. It wasn’t just the audience that had a good laugh; the world was in on the joke, too. Karla Sofia’s response was nothing short of iconic, and the memes that followed were equally as dramatic, funny, and savage as Conan’s quip.

It didn’t take long before social media users were dissecting every frame, every eyebrow raise, and every minor facial twitch that Karla Sofia made in response to O’Brien’s roast.

One of the earliest memes was a simple video captioned: "Karla Sofia Gascon after that Conan O'Brien Joke #Oscars2025."

People didn’t hold back, sharing this meme with captions full of side-eye and a hint of sympathy for the actress. It was clear that Karla Sofia had become an unwilling meme queen, and social media users were here for it.

Conan, of course, didn’t just stop at the initial joke. The memes kept rolling in as people picked up on his brutal yet hilarious line about Karla Sofia. One meme that took off included a caption saying, “Conan O’Brien dragged Karla Sofía Gascón to filth!”

Some Twitter users were practically in awe of how savage Conan could be in such a lighthearted setting. And naturally, the memes just kept coming.

One meme took it to the next level with the caption: "Karla Sofía Gascón after that Conan O’Brien joke," paired with an image of someone smoking a joint.

This meme gave off the vibe that Karla Sofia was too chill to care about Conan’s jab, even if deep down, we all knew it was a different story.

And let’s not forget the genius meme of "Karla’s publicist watching Conan O’Brien joke at the Oscars."

You could almost hear the collective gasp of publicists across the globe as they nervously texted their clients: “Handle this, stat.” Because, let’s be real, no one is ever fully prepared for the sheer chaos of an Oscar’s roast, least of all your publicist.

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At the end of the day, this moment at the Oscars is what makes social media and memes such a powerful force. What started as a simple joke has now turned into a viral phenomenon that will likely live on for years to come. Whether Karla Sofia was truly mad or just taking it in stride, we may never know, but what we do know is that Conan O’Brien’s roast will remain a highlight of the night, thanks to the internet's endless creativity.

In the world of the Oscars, where every moment is scrutinized and analyzed to the nth degree, sometimes it’s the funny little moments like Sofia’s reaction to Conan O’Brien that end up being the real stars of the show. So, here’s to more savage jokes, unforgettable reactions, and, of course, the endless stream of memes that remind us all why we love the internet.