Here are your General Hospital spoilers for Friday, March 21, 2025.
What to expect on General Hospital

Carly (Laura Wright) is tired of people telling her to stay away from Jack Brennan (Chris McKenna). She doesn't blame him at all for what happened and knows he technically had nothing to do with her being poisoned. This time it's Lucas (Van Hansis) who wants her to kick Jack out of her life, but Carly refuses. She blames Valentin and refuses to listen to anyone else say horrible things about Jack.
Jason (Steve Burton) blames Jack and thinks Valentin (James Patrick Stuart) can help him so he heads to his favorite spot in the PCPD interrogation room and even takes his chair and makes Valentin get in the other one. He demands to know everything that Valentin can tell him about Jack because he is determined to keep Carly away from him.
Nina gets desperate

Nina (Cynthia Watros) thought she had finally gotten through to Willow (Katelyn MacMullen) but Willow reverts to form once again. She is ready to move in with Drew (Cameron Mathison) and start a new life with him and her children.
An alarmed Nina once again tries to reason with her delusional daughter and tells her that she will hurt the children and her chance for custody of them if she moves in with Drew. Does Willow really want to risk losing them? Willow doesn't think that will happen, but Nina isn't so sure.
Nina realizes that she is going to have to resort to trickery to get Willow to wake up. If only Carly didn't get herself poisoned, so Nina and her frenemy have to delay putting their ultimate plan into action.
Drew never changes

Perhaps Nina should talk to her BFF Ava and learn that Drew has been blackmailing poor Portia (Brook Kerr). Drew is right back in Portia's office demanding more from her, but Portia fights back and tells Drew to take the win about the press conference.
Portia later updates Ava (Maura West) about her current Drew situation while Drew finds that he may have a new ally in town. Does he meet another politician who is as smarmy and corrupt as he is?
Catch all-new episodes of General Hospital weekdays on ABC and Hulu.

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