General Hospital Spoilers, April 29: Drew Cain won't know what hit him

Here are your General Hospital spoilers for Tuesday, April 29, 2025.

What to expect on General Hospital

Portia is ready to get down to business on General Hospital | Image: ABC

Drew (Cameron Mathison) thinks Portia (Brook Kerr) will keep doing his bidding and not fight back, but he is in for a rude awakening this week. As he makes more demands of Portia, she and Nina (Cynthia Watros) already have their plan in motion. Jacinda (Paige Herschell) is ready with that ketamine, and Portia and Nina will let the chips fall where they may.

Drew is set to make a scene on Tuesday, which people tend to do when they take this drug. Does he arrive at The Savoy and meet a blonde woman at the bar who distracts him with thoughts of how to manipulate Willow (Katelyn MacMullen) some more? Once Drew takes a drink, anything can happen...

More surprises at The Savoy

Professor Dalton gets around | Image: ABC

When Portia arrives at her husband's nightclub to see her handiwork in action, she isn't happy to spy Curtis (Donnell Turner) sitting at a table alone with Jordan (Tanisha Harper). Curtis warns Jordan to watch out for Sidwell (Carlo Rota).

Jordan is sure that she can get what she needs from Port Charles' latest master criminal, telling Curtis that it's not whether she can handle Sidwell. It's whether Sidwell can handle her.

At the bar, Anna (Finola Hughes) becomes more suspicious of Professor Dalton (Daniel Goddard) as she learns he used to teach at Berkeley, and Emma (Braedyn Bruner) is in his PCU class. However, Josslyn (Eden McCoy) makes sure to also get some alone time with Dalton and tells him how interested she is in that internship.

Gio's big surprise

Gio has some questions for Jason on General Hospital | Image: ABC

Gio (Giovanni Mazza) calls Emma over to the Q mansion to talk some sense into Tracy (Jane Elliot). Surely, Emma can make Tracy see that taking Sonny's (Maurice Benard) pier is the wrong thing to do. Tracy won't go down without a fight and reveals some shocking information to Gio that could change his perspective on everything.

When Gio talks to Jason (Steve Burton) about what he has learned, Jason tells the young man to just forget what he heard. But a seed has now been planted, and Gio is questioning everything he ever thought he knew. Will Sonny lose his grandson before Gio even learns they are related?

Catch all-new episodes of General Hospital weekdays on ABC and Hulu.