4) George O’Malley (Grey’s Anatomy)
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T.R. Knight left Grey’s Anatomy due to issues with his character’s reduced screen time. Knight reportedly felt sidelined and expressed frustration to showrunner Shonda Rhimes. A breakdown in communication between Knight and the creative team worsened the situation. Knight eventually asked to leave the series. His departure was finalized with George O’Malley’s heroic death in the season six premiere. The storyline gave closure but left fans divided. Many felt George’s arc deserved more attention. Knight later confirmed he felt staying on the show wasn’t beneficial to his career.
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Edited by Anshika Jain
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