6) Will Smith - The Matrix

Will Smith was offered the role of Neo in The Matrix but rejected it and famously admitted, "I didn't get it, to be honest." Meanwhile, Smith continued concentrating on other, more salient, 'classic' roles, such as Wild Wild West and thought that Neo was outside his comfort zone. Keanu Reeves eventually ended up filling the role as the portrayal of Neo became legendary, helping establish The Matrix as a science fiction legend. Smith, on the other hand, went on to star in box office successes such as Men in Black and Independence Day.
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Edited by Apoorva Jujjavarapu