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7. Helena Cassadine (General Hospital)
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Helena, matriarch of havoc in Port Charles, is played by Constance Towers. With her cold gaze and devilish smile, Helena brings havoc into the lives of those around her. Towers' iconic performance brings depth and complexity to the character, making Helena a legendary GH villain. Helena first appeared on General Hospital in 1981, portrayed by the legendary actress Elizabeth Taylor. Later, from 1997 to 2023, Constance Towers played the role.
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Edited by Anshika Jain
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