Joe leaves a very sick looking Neil and runs into Chris in the hall. Chris seems genuinely concerned and Joe fills him in on Neil's state. Chris told Joe that Neil is a terrific kid and told Joe to let him know if there is anything he can do. Neil heads down to the lab and offers to help Matt. Matt is very snarky to him, apparently personal feelings are more important than letting a skilled doctor help save a child's life, and refuses his offer. Out in the hall, Eve comes up to Chris and told him Joe's patients are less grumpy that hers. Chris teases her about taking over for Karen and Joe. Eve has heard that Chris offered to help as well. He thinks the hospital must be hard up for gossip, Eve told him that it's news when he's being altruistic. Chris told her he likes Neil, and told her he's heading home to his beautiful and innocent wife. The banter about sex and Eve realizes that Chris and Julie haven't made love yet. Eve warns him that black widows kill after mating. Chris leaves and she calls after him that she's not kidding.
Kevin is telling Victor on the phone that he wants to change all the locks on the house - he thinks someone has access. Eve, having just come in, overhears and says "WHAT?" Kevin hangs up and Eve is upset - she thinks Kevin thinks that Julie has her lost keys. They discuss Neil. Kevin is going to see him and Eve decides to go along to see if she can pick up some shifts for Joe and Karen to free them up. She mentions Chloe (from GH) getting hit by a car and says it really puts their problems in perspective.
Matt and Karen have apparently been up forever working on the blood samples. Matt convinces Karen to take a break - the camera scans to the vials of blood. She talks to Joe about Neil and options. Joe desperately grabs at straws while Karen remains realistic. Joe denies being non-objective, Karen suggests he take himself off Neil's case. They argue and Joe accuses Karen of a lack of faith in him.
Rachel arrives at her office as the phone starts to ring. She looks apprehensive, but answers - it's Julie. She's been trying to get Rachel all night (Rachel says she has some things to take care of) - she's worried about Kevin. Julie comes to the office and they discuss her adjusting to freedom. Julie told Rachel about running into Eve and Kevin at Lucy's. Rachel told her to trust her - she'll take care of Kevin and get Christina back. Rachel says Chris is blowing their chances though. Julie wonders why Rachel is coming down so hard on Chris. Julie says she was with Chris all along. She says there's one thing she disagrees with - having Christina tested for a bone marrow match. Julie worries that they'll discover Frank is her biofather and that will lead to her. Rachel stresses that Chris went against Julie's strong wishes to get Christina tested. Julie defends the action, that Dr. Chris just wants to help a sick child.
Chris arrives home - Julie has made him a martini. He pronounces it perfect, she can't tell because she thinks they taste like gasoline. Julie wants to hear about his day and work, she needs conversation. They move to Neil and Christina and the mood darkens as Julie asks if he doesn't care about her feelings about the testing and possible matching. They both decide to retire for the night. Chris told her she can stay in his room again, but she claims she's still adjusting and heads to her own.
Kevin wasn't able to see Neil, and Eve told him to hold on, she's just finishing up. She heads off to check her mail and Rachel comes up and bitches at Kevin about his run-in with Julie. Rachel leaves and Eve returns - she found her keys in her mailbox and guesses she just replaced them.
Joe visits the sleeping Neil and encourages him to hold on. Meanwhile in the lab, Karen told Matt to take a break. The camera pans to Christina's vial of blood which is FINALLY is Karen's hands. She told it, you're next - let's see what you're made of baby!
At the Firehouse, Scott, on the phone with Karen, is checking on Neil's condition. When he hangs up, Lucy asks about Neil and Scott told her - he's worse. Scott told her he thinks it's touch and o for Neil Serena, overhearing, asks if Neil is gonna die.
At the hospital, Courtney is telling Frank that they need to spend as much time with Neil as they can. Now. Franks says Neil doesn't want to see him and he's so sick... Courtney says that's the point; he IS very ill and that's why she needs Frank with her. There may not be a lot of time. Frank accompanies her into Neil's room. As Courtney adjusts Neil's pillows she notices a rash on his ears and eyelids and that he's burning up with fever. Neil starts to breathe heavily and says he can't breathe. Franks runs for help and Courtney stays and pleads with Neil to hang on. Joe and Karen run in and go to work; Neil is having a transfusion reaction. They get him stabilized and Joe asks Courtney and Frank to go into the hall to talk. He told them It appears that Neil is having a reaction to the blood and that they have to run some tests to see if his kidneys are working right. He explains that it's a domino effect; the drug made him anemic requiring transfusions which in turn may have damage his kidneys. Joe went back into Neil's room and Courtney and Frank embrace.
At the Firehouse, Lucy and Scott are talking to Serena about Neil She says she already has made plans with Neil! Scott uses an analogy of a time when she got swept under while swimming in the ocean and how with each wave, it got harder to fight. But, Serena says, they made plans to go snowboarding and she told him Scott could get tickets to the a baseball game. Scott says he probably could get tickets. It's not too late. But Serena says he won't. She says she spoke to "mommy's star" last night and asked her to help Neil get better. She says that if Neil dies, she'll never talk to his star because if she can't see him, it just wouldn't be the same. At the hospital, Karen and Joe tell Courtney and Frank that Neil's kidneys have failed and that he'll need dialysis to give them a rest. They get ready to do it then and Frank and Courtney leave. Joe told Karen to go work on the donor blood, he can do this. She says okay. He turns around and told her really. Neil has to have a donor. He's running out of time.
Frank and Courtney are in the Chapel; she's lost her hope and feels God isn't listening. She says Neil's never been so close to death and she just wants to scream at the sky - Make him well! Frank says maybe she should. If it'll help. He says he loves her and Neil and, no matter what happens, they'll get through it together. She says God should take her instead. She turns and asks that she be taken and Neil allowed to live. They embrace.
Scott and Lucy, at the Firehouse, are talking about Neil - and Serena. Scott says there's got to be something they can do. Lucy says they need a miracle. Scott asks how a small miracle would do... In Neil's room, Courtney and Frank are with Neil when Serena enters. She says she has a surprise for Neil. He perks up and asks what? Serena went to the door and beckons someone in. Neil's face went even whiter and then joy starts. His surprise is Eric Karros, his favorite Dodger! They chat for a while, Serena beaming and watching, and Eric gives Neil the bat he hit 34 homers with. He also invites Neil to be his guest at a Dodgers game - and Serena too, of course. Eric told Neil he has a good team - and that's important. Courtney and Frank excuse themselves to thank Scott and Lucy. Courtney tells them this gives her hope.
In the lab, Karen and Matt are still testing donor blood. Karen says it's like everything makes Neil worse. Karen picks up a chart to check it and it's a close match for Neil, It's Christina's blood.