Scott was frantic when he couldn't find Serena. Shortly thereafter, however, Scott found Serena hiding under some bushes in the yard. Serena told Scott that she had run off because she was afraid that the "bad people" would take her away from Scott. Lucy, Scott and Gail then comforted Serena. Eve and Scott continued to bond and Lucy wasn't too pleased to learn that Eve was doing her best to comfort Scott. Later, Lucy shared her anxiety with Kevin over her upcoming fertility tests. Bennett offered a large reward for Julie's safe return and Chris bought a billboard to advertise Julie's disappearance and the reward. Frank and Garcia questioned a hospital orderly whose ID had been stolen on the night Julie disappeared. Garcia and Frank also spoke to a security guard who remembered that he had encountered an orderly who had been using the ID in question as he was taking a body to the morgue. Frank and Bennett later learned that no body had been delivered to the morgue on the night Julie disappeared and they wondered if the phony orderly had taken Julie out of the hospital on a gurney. Meanwhile, Cooper was ready to start Julie's surgical makeover. Julie resisted and knocked over a bottle of anesthetic Cooper needed for the surgery. A furious Cooper then left to get more anesthesia as Julie prayed that she would be rescued before he returned.
Scott had a frustrating confrontation with Rex and Danielle over the custody suit. Scott then took Serena away alone without getting the approval of the social worker or Lee and Gail. Later, Gail called Lucy and told her that Scott and Serena were missing. Fearing that Scott had fled the country with Serena, Lucy asked Karen for her help in locating them. Meanwhile, Karen confronted Jake about his involvement in Rex and Danielle's scheme to get custody of Serena. Garcia arrived at the hospital with a police sketch of the man suspected of kidnapping Julie that had been obtained with the help of a photo developer who had remembered developing pictures of Julie. All of the interns were shocked when the man in the sketch turned out to be Cooper. Audrey finally realized that Cooper had been the orderly she encountered in the hall on the night Julie disappeared. Meanwhile, Cooper sneaked into the hospital to steal more anesthesia and overheard Audrey telling Mary that the police had a sketch of Cooper. Eve found a patients watch in her locker and initially accused Chris of planting it there. Soon, however, the interns realized that the plot to discredit them continued. Lucy and Kevin met with Dr. Neumann, who gave them the troubling news that Lucy might have problems conceiving another child and carrying it to term.
At the coffeehouse, Devon spilled his drink. Kay approached him and asked if he needed a hand. Devon said he was just clumsy. Kay offered to help Devon if he ever needed a hand.
Frank and Chris were convinced that Cooper was still alive and was somehow responsible for Julie's disappearance. Detective Garcia then agreed to contact the coroner, despite evidence saying that Cooper was dead. Later, Garcia confirmed Frank's suspicions when he was unable to find irrefutable evidence that Cooper had died in the explosion. Mary told Garcia the story about the strange disappearance of Father Wysocki and Garcia started to investigate. Meanwhile, Julie remained locked in the basement while Cooper made his way to the supply room in the hospital to steal more anesthetic. While trying to break into the supply room, however, Cooper was stopped by a guard and was forced to flee. Lucy and Karen found Scott and Serena at the gazebo. While Karen occupied Serena, Lucy blasted Scott for considering fleeing with Serena. Scott and Lucy then reiterated the importance of their friendship to one another. Mac called Lucy on her cell phone and Scott and Lucy learned that Mac had tracked down the casino owner who had framed Scott. Scott, however, was unaware that someone was taking his picture as he spent time with Serena during their illegal visit. A gleeful Rex spied on Danielle through his surveillance system as she snooped about his study. Rex then toyed with Danielle and told her that he wanted to create a nurturing environment for everyone, including Serena.