The four-time Emmy nominated actress began her television career as a regular on another ABC Daytime series, A Time for Us. She also spent two-and-a-half years on the CBS Daytime series, Love Is a Many Splendored Thing, where she garnered her first Emmy nomination for the role of Iris Donelly Garrison.
Of all the numerous commercials Leslie has done, she credits those for Pearl Drops with getting her a part in the movie Day of the Dolphin, directed by Mike Nichols and co-starring George C. Scott. She followed this with a performance in the David Merrick play, one-night stand, co-starring Tony Curtis.
After that, Charleson moved to Hollywood and guest-starred on more than twenty TV series, including Adam 12; Barnaby Jones; The Streets of San Francisco; Medical Center; The FBI; Marcus Welby, M.D;, Ironside; Kung Fu; Wild Wild WestEmergency; Baa Baa Black Sheep; Cannon; and The Rockford Files. It was on Happy Days that Leslie gave Ron Howard his first on-screen kiss. She also co-starred with Deidre Hall in the television movie, Woman on the Ledge, and made a guest appearance on Diagnosis Murder and Dharma & Greg.
Ms. Charleson is an active celebrity spokesperson for breast cancer, cystic fibrosis, and AIDS-related charities. She lives in the Los Angeles area.