Cameron came to town in the spring of 2012. He met Celeste at the hospital. Celeste introduced Cameron and revealed that he was Lexie's half-brother. Celeste explained that Cameron had been taken away from her when he was five years old, and she had not mentioned him before because the situation was too painful to talk about.
With a smile, Cameron said that he had met Lexie before. Cameron showed the framed photograph to Lexie. The photo was of Lexie, Cameron, and Celeste. Fighting tears, Lexie noted that the picture had been taken back when she believed Celeste was her aunt. Celeste explained that Cameron was also a doctor, like Lexie.
Cameron also had a flirtatious run-in with Abigail on his fist day in Salem. Their flirtation continued the next several times they met. Eventually, the two began dating. She helped him through the loss of his sister, Lexie. And, he got the seal of approval from both Jack and Jennifer.
The night of an autism benefit in Lexie's honor, there was a huge explosion in the tunnels underneath Salem. Abigail and Jack were trapped in the elevator. Cameron and Jennifer worked to free them. Abigail got out, but the elevator broke before Jack could escape as well. Jack died in the accident.
Heartbroken by her father's death, Abigail threw herself into her relationship with Cameron. But, when Cameron felt that Labial was trying to deal with her grief by wanting to have sex with him, he broke things off with Abigail.
He went on a few dates with a woman named Emily, but that relationship did not last. Soon, he got back involved with Abigail. Abigail was embarrassed when Cameron found out that she had been a member of the "Golden Circle" club in high school -- a group of kids who promised to wait to have sex until they were married. But Cameron assured Abigail that they could take their relationship at her pace.
But, Cameron was still keeping a secret from Abigail. He was working a second job as a stripper to make money to pay off one of Celeste's debts. When Abigail found out about it, she was shocked, but more concerned that if Anne Milbauer from HR found out about it, she would have Cameron fired. So, Abigail arranged for Anne to be present on a night when several of Salem's men (Rafe, Cameron, Daniel, and Brady) would strip to raise money for a new wing at the hospital. When the hospital board heard how much money was raised, they dismissed Anne's objection.
But, things weren't perfectly smooth for Cameron and Abigail, as Chad had since made it known to Abigail that he was interested in her too. Both guys agreed to give Abigail the time to figure out which guy she wanted to be with. On the Fourth of July, Chad fell and hit his head, causing Cameron to insist that Chad have it checked out. When Cameron looked at the scans of Chad's head, Cameron told Chad that there was an indication of a brain tumor and urged Chad to see a specialist.
Chad got a clean bill of health, but told Cameron that he did have a brain tumor. Cameron backed off Abigail and urged her to spend more time with Chad. Abigail and Chad grew closer and Cameron went on a few casual dates with Gabi. But when Chad got shot and went into emergency surgery, E.J. was forced to come clean and let Cameron know that Chad wasn't on any drug protocols because Chad didn't have a tumor. Cameron told Chad to come clean with Abigail.
Chad told Abigail the truth. She broke up with him almost immediately and then went to confront Cameron about turning her over to Chad without a fight. Cameron tried to apologize, but Abigail was furious. A few days later Cameron got a job offer from Doctors Without Boarders. He accepted the position and left Salem.