Seganti returned to As the World Turns in March 2009. At the time, a show source told Soap Central that Damian's return to Oakdale was an attempt to boost the show's ratings. It had been more than two years since the actor last appeared on As the World Turns.
In addition to his work in daytime, Seganti has also found success outside the soaps. He has appeared in several feature films, including L.A. Confidential and Tea with Mussolini.
Seganti originated the role of Damian Grimaldi in 1993.